Ephylone, BK-Ethyl-K, BK-EBDP
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Ephylone which also goes by the names BK-Ethyl-K and BK-EBDP is a chemical from the class substituted cathinones. It is part of a wave of substituted cathinones which have emerged in recent years for which there is little information available on human consumption. Ephylone is the N-methyl analogue of the cathinone pentylone.
Ephylone goes by the formal and systematic IUPAC name (benzo[d][1,3]dioxo1-5-y1)-2-(ethylamino)pentan-1-one, has an empirical molecular formula C14H19NO3 and a molar mass of 250 grams.
The substituted cathinones are a chemical series that tend to have stimulatory psychoactive effects in humans. Their defining characterisitics are a phenethylamine backbone with an alkyl substituent at the alpha carbon next to the nitrogen and a ketone at the beta carbon. They all have a structural resemblance to cathinone which is a naturally occurring plant based chemical found in the ethnobotanical drug Khat derived from the leaf of Catha edulis native to the horn of Africa. Khat has a long history of use in this region. The leaf is chewed to release the active alkaloids producing a mild and pleasant stimulatory effect, feelings of energy and talkativeness and markedly suppressed appetite.
One of the most famous and widely abused derivatives of cathinone is mephedrone otherwise known as 4 MMC. It gained popularity at a time of increasing shortages of quality MDMA as a chemical that could produce feelings of euphoria, empathy and stimulation similar to street drugs “Ecstasy” and cocaine.
Pentylone, another member of the cathinone family, acts as a serotonin-norepinepherine-dopamine reuptake inhibitor and mild serotonin releasing agent. Owing to the structural similarity of pentylone to ephylone and the dearth of quality information regarding ephylone it is worth outlining the properties of pentylone which may have similar effects. All members of the cathinone class act as norephedrine reuptake inhibitors. Individual members of the class vary in their propensity towards either serotonin or dopamine reuptake inhibition. Further to this some members of the class are more likely to release monoamines than others. To illustrate, mephedrone is a more potent serotonin reuptake inhibitor and will release serotonin in a fashion similar to the party drug MDMA. Pentylone and 4 MEC by contrast inhibit reuptake of all three monoamines to an equal degree and releases serotonin more weakly.
Ephylone/ BK-Ethyl-K/ BK-EBDP differs in structure from pentylone by having an ethyl instead of a methyl substituent at the nitrogen. Both compounds have a dioxymethyl group fused to the benzene ring and a propyl alkyl chain substituted at the alpha position. However it is worth noting that even tiny adjustments to structure can have huge effects of chemicals at binding sites.
Human toxicological, physiological and pharmacological data for ephylone is not available. It has not even been tested on rats and its binding affinities in vivo are untested. Therefore this is a highly novel chemical entity with no reliable scientific information published about it.
It is not for animal or human consumption.
There are few online reports of use and such reports are not verifiable. They suggest ephylone produces a mild stimulatory effect.