Buy MMB-2201 Powder online – MMB-2201 Powder


Chemical Data :

IUPAC: (S)-methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3-methylbutanoate


ChemSpider: N/A

Molecular Weight: 362.437 g/mol

Molecular Formula: C20H27FN3O3

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MMB 2201

MMB 2201 is a potent synthetic cannabinoid of the indole class. Its structure contains an indole-3-carboxamide moiety. MMB-2201 is also listed known the various names 5F-MMB-PICA, 5F-AMB-PICA and I-AMB

MMB-2201 bears a close structural similarity to the potent cannabinoid AM2201. Bothcompounds contain a 1-(5-fluoropentyl)-indole-3-keto moiety. The naphthalene inAM2201 is replaces with a methyl valinate to produceMMB2201. It may also be described as an indole analogue of the indazole cannabinoid 5F AMB.

MMB-2201 is classified under the formal and systematic IUPAC name methyl (1-(5-fluoropentyl)-1H-indole-3-carbonyl)-L-valinate. The compound has a relative molar mass of 362.5 grams, forms a crystalline solid at room temperature and pressure and has the empirical molecular formula C20H27FN2O3.

In recent years there has been a surge in the availability and use of synthetic cannabinoids with an indazole or indole ring structure combined with amino acid side chains L-valinamide or L-tert-leucinamide. This is part of a larger trend of a multitude of new synthetic cannabinoids being produced which is unprecedented. The effect on human health of the majority of these emerging psychoactive compounds remains largely unknown. 

Worryingly there is a trend towards increasing potency with each new generation. The production of a multitude of synthetic cannabinoid agents has been spurred on by legislation banning older generations of the compounds. In a phenomenon described as “whack a mole” banning of one set of analogues forces clandestine laboratories to produce new analogues. This trend is aided by the relative ease of synthesis of the synthetic cannabinoids many of which can be produced in a two stage process with one purification stage.

There is scientific literature which reports on the pharmacology of MMB 2201. It is a highly potent and full agonist at human cannabinoid receptor CB1 with an EC50 value below 0.24 nM. It has been shown to induce bradycardia (reduced heart rate) and hypothermia in rats within the dose range 0.2 – 3 mg / Kg. The action of MMB 2201 is reversed by pre-treatment of rats with a known cannabinoid antagonist providing experimental proof of its cannabinoid status and corroborating the reported psychoactive effects in humans similar to herbal cannabis.

However THC,the primary psychoactive component of herbal marijuana, is a comparably benign substance compared to the powerful synthetic cannabinoids such as MMB 2201. THC is a partial agonist compared to the full and potent agonist MMB 2201. This gives it a more severe profile of effects which are much stronger than traditional herbal cannabis.  The problem with this is that MMB-2201 then has potential for overdose, seizure, severe intoxication and death unlike marijuana.

MMB 2201 remains untested in humans. It is not fit for animal or human consumption.

Purely subjective online reports claim that MMB 2201 is highly potent and sedating. Effects can be overpowering mentally and physically. Active doses are reported in the sub 10 mg range. It is recommended that doses are measured using volumetric dosing techniques and mg scales.  Vaporisation by heat methods will produce harmful chemicals by thermal degredation that are toxic to the lungs and brain.

Properties Of MMB-2201

Density: 1.2±0.1 g/cm3
Boiling Point: 552.9±40.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.5 mmHg at 25°C
Enthalpy of Vaporization: 83.4±3.0 kJ/mol
Flash Point: 288.2±27.3 °C
Index of Refraction: 1.543
Molar Refractivity: 99.0±0.5 cm3
#H bond acceptors: 5
#H bond donors: 1
#Freely Rotating Bonds: 10
#Rule of 5 Violations: 0
ACD/LogP: 3.71
ACD/LogD (pH 5.5): 3.52
ACD/BCF (pH 5.5): 280.10
ACD/KOC (pH 5.5): 1965.12
ACD/LogD (pH 7.4): 3.52
ACD/BCF (pH 7.4): 280.10
ACD/KOC (pH 7.4): 1965.12
Polar Surface Area: 60 Å2
Polarizability: 39.3±0.5 10-24cm3
Surface Tension: 37.7±7.0 dyne/cm
Molar Volume: 314.3±7.0 cm3

Other names and synonyms for MMB-2201 Powder:

L-Valine, N-[[1-(5-fluoropentyl)-1H-indol-3-yl]carbonyl]-, methyl ester [ACD/Index Name]
Methyl N-{[1-(5-fluoropentyl)-1H-indol-3-yl]carbonyl}-L-valinate [ACD/IUPAC Name]
Methyl-N-{[1-(5-fluorpentyl)-1H-indol-3-yl]carbonyl}-L-valinat [German] [ACD/IUPAC Name]
N-{[1-(5-Fluoropentyl)-1H-indol-3-yl]carbonyl}-L-valinate de méthyle [French] [ACD/IUPAC Name]
methyl (1-(5-fluoropentyl)-1H-indole-3-carbonyl)-L-valinate
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  • 5g : 85 | 10g : 120 | 50g : 300 USD | 100g : 400 USD | 250g : 600 USD | 500g : 1000 USD |1kg : 1800 USD


Full Chemical Data Of  MMB-2201

IUPAC: methyl (2S)-2-{[1-(5-fluoropentyl)-1H-indol-3-yl]formamido}-3-methylbutanoate

Smiles: COC(=O)[C@@H](NC(=O)C1=CN(CCCCCF)C2=CC=CC=C12)C(C)C

InChI: 1S/C20H27FN2O3/c1-14(2)18(20(25)26-3)22-19(24)16-13-23(12-8-4-7-11-21)17-10-6-5-9-15(16)17/h5-6,9-10,13-14,18H,4,7-8,11-12H2,1-3H3,(H,22,24)/t18-/m0/s1


Formula: C20H27FN2O3
Isotope formula: C20H27FN2O3
Composition: C (66.28%), H (7.51%), F (5.24%), N (7.73%), O (13.24%)
Isotope composition: C (66.28%), H (7.51%), F (5.24%), N (7.73%), O (13.24%)
Mass: 362.4384
Exact mass: 362.200570945

Atom count: 53
Bond count: 54
Cyclomatic number: 2
Chain atom count: 17
Chain bond count: 17
Asymmetric atom count: 1
Rotatable bond count: 10
FSP3: 0.50

Ring Count: 2
Ring atom count: 9
Ring bond count: 10
Aliphatic ring count: 0
Aromatic ring count: 2
Aliphatic atom count: 17
Aliphatic bond count: 17
Aromatic atom count: 9
Aromatic bond count: 10
Carbo ring count: 1
Hetero ring count: 1
Heteroaromatic ring count: 1
Carboaromatic ring count: 1
Fused ring count: 2
Fused aliphatic ring count: 0
Fused aromatic ring count: 2
Largest ring size: 6
Smallest ring size: 5

Platt index: 72
Randic index: 12.49
Balaban index: 1.97
Harary index: 93.98
Wiener index: 1764
Hyper Wiener index: 7154
Wiener polarity: 39
Szeged index: 2199

Lipinski’s rule of five: yes
Bioavailability: yes
Ghose filter: yes
Lead likeness: yes
Muegge filter: yes
Veber filter: yes

Additional information


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